Article
Long noncoding RNA NORAD regulates transforming growth factor-β signaling and epithelial-to-mesenchymal transition-like phenotype.
Cancer science - 1 Jul 2018
Kawasaki Natsumi, Miwa Toshiki, Hokari Satoshi, Sakurai Tsubasa, Ohmori Kazuho, Miyauchi Kensuke, Miyazono Kohei, Koinuma Daizo
Abstract excerpt
Long noncoding RNAs are involved in a variety of cellular functions. In particular, an increasing number of studies have revealed the functions of long noncoding RNA in various cancers; however, their precise roles and mechanisms of action remain to be elucidated. NORAD, a cytoplasmic long noncoding RNA, is upregulated by irradiation and functions as a potential oncogenic factor by binding and inhibiting Pumilio...
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