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High long non-coding RNA NORAD expression predicts poor prognosis and promotes breast cancer progression by regulating TGF-β pathway

20 Mar 2019

Abstract excerpt

BACKGROUND: To investigate the expression and significance of long noncoding RNA NORAD (lncRNA-NORAD) in breast cancer. METHODS: Q-PCR was adopted to detect the mRNA expression of lncRNA-NORAD in breast cancer and adjacent tissues, survival analysis to compare the low-expression groups with the Kaplan-Meier method. Knockout of lncRNA-NORAD was adopted to observe the effects on the cell proliferation, migration...

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PMID: 30930692
DOI: 10.1186/s12935-019-0781-6

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