Article
In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype.
Molecular biology of the cell - 1 Jul 2018
Walker J L, Bleaken B M, Romisher A R, Alnwibit A A, Menko A S
Abstract excerpt
Following injury, mesenchymal repair cells are activated to function as leader cells that modulate wound healing. These cells have the potential to differentiate to myofibroblasts, resulting in fibrosis and scarring. The signals underlying these differing pathways are complex and incompletely understood. The ex vivo mock cataract surgery cultures are an attractive model with which to address this question. With...
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