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Article

Transforming growth factor-beta-induced epithelial-mesenchymal transition in the lens: a model for cataract formation.

Cells, tissues, organs - 1 Jan 2005

de Iongh R U, Wederell E, Lovicu F J, McAvoy J W

Abstract excerpt

The vertebrate lens has a distinct polarity and structure that are regulated by growth factors resident in the ocular media. Fibroblast growth factors, in concert with other growth factors, are key regulators of lens fiber cell differentiation. While members of the transforming growth factor (TGFbeta) superfamily have also been implicated to play a role in lens fiber differentiation, inappropriate TGFbeta...

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Identifiers

PMID: 15942192
DOI: 10.1159/000084508

Genes

ILK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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