Multivariate analysis for coronary heart disease in heterozygote familial hypercholesterolemia patients.

doi:10.2217/pme-2017-0075

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Article

Multivariate analysis for coronary heart disease in heterozygote familial hypercholesterolemia patients.

Personalized medicine - 1 Mar 2018

Sánchez Muñoz-Torrero Juan Francisco, Rivas Maria D, Zamorano Jose, Joya-Vázquez Pedro Pablo, de Isla Leopoldo Perez, Padro Teresa, Mata Pedro, The Safeheart Investigators

Abstract excerpt

AIM: rs599839 polymorphism has been related with low levels of cholesterol and reduced coronary heart disease (CHD). METHODS: We investigated the frequency of this polymorphism in patients with heterozygous familial hypercholesterolemia (HeFH) in the Spanish familial hypercholesterolemia cohort, 230 with and 202 without CHD. Results & discussion: A lower G-allele prevalence was observed in HeFH patients with CHD...

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PMID: 29714125
DOI: 10.2217/pme-2017-0075

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