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Article

Apolipoprotein E Gene Variants and Risk of Coronary Heart Disease: A Meta-Analysis.

BioMed research international - 1 Jan 2016

Xu Min, Zhao Jun, Zhang Yu, Ma Xu, Dai Qiaoyun, Zhi Hong, Wang Bei, Wang Lina

Abstract excerpt

Objectives. Apo E genes involved in lipoprotein synthesis and metabolism are considered one of the candidates to CHD. However, the results remain conflicting. Methods. We performed this meta-analysis based on 30 published studies including 11,804 CHD patients and 17,713 controls. Results. Compared with the wild genotype E3/3, the variant genotypes ApoEE3/4 and E4/4 were associated with 22% and 45% increased risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27868062
DOI: 10.1155/2016/3912175
PMCID: PMC5102878

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