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Article

Risk factors for atherosclerotic cardiovascular disease in individuals with heterozygous familial hypercholesterolemia: a systematic review and meta-analysis.

Atherosclerosis - 1 Apr 2026

Mansilla-Rodríguez María Elena, Sánchez-Ramos José Luis, Sánchez-Junco Alina Rigabert, Pang Jing, Chan Dick C, Gutiérrez-Cortizo Eva Nadiejda, Mata Pedro, Watts Gerald F, Romero-Jiménez Manuel Jesús

Abstract excerpt

BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is a highly prevalent monogenic disorder characterized by elevated low-density lipoprotein-cholesterol (LDL-C) levels and premature atherosclerotic cardiovascular disease (ASCVD). The risk factors associated with cardiovascular events in this population vary considerably among studies. This systematic review aims to identify the key risk factors predicting...

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Identifiers

PMID: 42025352
DOI: 10.1016/j.atherosclerosis.2026.120650

Genes

FH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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