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Article

Ancestry-independent risk of venous thromboembolism in individuals with sickle cell trait vs factor V Leiden.

Blood advances - 12 Nov 2024

Lin Keng-Han, Granka Julie M, Shastri Anjali J, Bonham Vence L, Naik Rakhi P

Abstract excerpt

ABSTRACT: Sickle cell trait (SCT) is a risk factor for venous thromboembolism (VTE). Prior studies investigating the association between SCT and VTE have been performed nearly exclusively in Black populations. However, race-based research can contribute to systemic racism in medicine. We leveraged data from the 23andMe research cohort (4 184 082 participants) to calculate the ancestry-independent risk of VTE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39255335
DOI: 10.1182/bloodadvances.2024014252
PMCID: PMC11570785

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