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Article

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma.

Nature communications - 27 Apr 2018

Manier S, Park J, Capelletti M, Bustoros M, Freeman S S, Ha G, Rhoades J, Liu C J, Huynh D, Reed S C, Gydush G, Salem K Z, Rotem D, Freymond C, Yosef A, Perilla-Glen A, Garderet L, Van Allen E M, Kumar S, Love J C, Getz G, Adalsteinsson V A, Ghobrial I M

Abstract excerpt

Liquid biopsies including circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have enabled minimally invasive characterization of many cancers, but are rarely analyzed together. Understanding the detectability and genomic concordance of CTCs and cfDNA may inform their use in guiding cancer precision medicine. Here, we report the detectability of cfDNA and CTCs in blood samples from 107 and 56 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29703982
DOI: 10.1038/s41467-018-04001-5
PMCID: PMC5923255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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