Article
Tracking myeloma tumor DNA in peripheral blood.
Best practice & research. Clinical haematology - 1 Mar 2020
Waldschmidt Johannes M, Vijaykumar Tushara, Knoechel Birgit, Lohr Jens G
Abstract excerpt
Over the past years, the emergence of liquid biopsy technologies has dramatically expanded our ability to assess multiple myeloma without the need for invasive sampling. Interrogation of cell-free DNA from the peripheral blood recapitulates the mutational landscape at excellent concordance with matching bone marrow aspirates. It can quantify disease burden and identify previously undetected resistance mechanisms...
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