Article
Interactions Among Polymorphisms of Susceptibility Loci for Alzheimer's Disease or Depressive Disorder.
Medical science monitor : international medical journal of experimental and clinical research - 28 Apr 2018
Kitzlerová Eva, Fišar Zdeněk, Lelková Petra, Jirák Roman, Zvěřová Martina, Hroudová Jana, Manukyan Ada, Martásek Pavel, Raboch Jiří
Abstract excerpt
BACKGROUND Several genetic susceptibility loci for major depressive disorder (MDD) or Alzheimer's disease (AD) have been described. Interactions among polymorphisms are thought to explain the differences between low- and high-risk groups. We tested for the contribution of interactions between multiple functional polymorphisms in the risk of MDD or AD. MATERIAL AND METHODS A genetic association case-control study...
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