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Article

BDNF genetic variations increase the risk of Alzheimer's disease-related depression.

Journal of Alzheimer's disease : JAD - 1 Jan 2009

Borroni Barbara, Grassi Mario, Archetti Silvana, Costanzi Chiara, Bianchi Marta, Caimi Luigi, Caltagirone Carlo, Di Luca Monica, Padovani Alessandro

Abstract excerpt

The gene encoding the brain-derived neurotrophic factor (BDNF) has been demonstrated as a candidate for Alzheimer's disease-related depression (AD-D) susceptibility. Additionally, an association between AD-D and the functional valine to methionine (Val66Met) polymorphism has been reported. The aim of this study was to assess the genetic contribution of other BDNF variants to AD-D. Two-hundred forty-five AD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19661618
DOI: 10.3233/JAD-2009-1191

Genes

BDNF

Variants

rs2049045
rs2049045
rs2049045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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