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Article

DNA damage pathways and B-cell lymphomagenesis.

Current opinion in hematology - 1 Jul 2018

Knittel Gero, Rehkämper Tim, Nieper Pascal, Schmitt Anna, Flümann Ruth, Reinhardt H Christian

Abstract excerpt

PURPOSE OF REVIEW: Recent lymphoma genome sequencing projects have shed light on the genomic landscape of indolent and aggressive lymphomas, as well as some of the molecular mechanisms underlying recurrent mutations and translocations in these entities. Here, we review these recent genomic discoveries, focusing on acquired DNA repair defects in lymphoma. In addition, we highlight recently identified actionable...

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Share to Ataxia Telangiectasia Mutated Proteins
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Activated Protein Kinase

Share to DNA Damage

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to Poly (ADP-Ribose) Polymerase-1

Source

Identifiers

PMID: 29702521
DOI: 10.1097/MOH.0000000000000433

Genes

ATM
PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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