Article
Germline variants of DNA repair and immune genes in lymphoma from lymphoma-cancer families.
International journal of cancer - 1 Jul 2024
Wang Xiaogan, Deng Lijuan, Ping Lingyan, Shi Yunfei, Wang Haojie, Feng Feier, Leng Xin, Tang Yahan, Xie Yan, Ying Zhitao, Liu Weiping, Zhu Jun, Song Yuqin
Abstract excerpt
The genetic predisposition to lymphoma is not fully understood. We identified 13 lymphoma-cancer families (2011-2021), in which 27 individuals developed lymphomas and 26 individuals had cancers. Notably, male is the predominant gender in lymphoma patients, whereas female is the predominant gender in cancer patients (p = .019; OR = 4.72, 95% CI, 1.30-14.33). We collected samples from 18 lymphoma patients, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.