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Article

Rapid Gene Concatenation for Genetic Rescue of Multigene Mutants in Candida albicans.

mSphere - 25 Apr 2018

Huang Manning Y, Woolford Carol A, Mitchell Aaron P

Abstract excerpt

The biological function of a gene is often probed through its interactions with other genes. This general approach has been especially useful to build knowledge about poorly understood genes upon the bedrock of well-characterized genes. Genetic interaction analysis requires the construction of strains with mutations in two or more genes. Single-gene mutants of microbial pathogens are generally validated through...

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Identifiers

PMID: 29695626
DOI: 10.1128/mSphere.00169-18
PMCID: PMC5917427

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Source receipt: pubmed, retrieved 7 Sept 2026.

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