Article
Virological characterization of HIV-1 CA-NTD mutants constructed in a virus-lineage reflected manner.
The journal of medical investigation : JMI - 1 Jan 2018
Nakanishi Shoko, Watanabe Sakimi, Doi Naoya, Koma Takaaki, Adachi Akio, Nomaguchi Masako
Abstract excerpt
Capsid (CA) protein is a major virion-constituent of all retroviruses including human immunodeficiency virus type 1 (HIV-1), and is essential for early and late phases in viral replication cycle through interaction with numerous cellular factors. In particular, N-terminal domain (NTD) of HIV-1 CA has been frequently and well reported to bind to various host cell proteins that considerably affect viral replication...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
