Article
No association between 5 new GWAS-linked loci in Parkinson's disease and multiple system atrophy in a Chinese population.
Neurobiology of aging - 1 Jul 2018
Chen Yongping, Cao Bei, Gu Xiaojing, Ou Ruwei, Wei Qianqian, Liu Hui, Zhang Lingyu, Yuan Xiaoqin, Song Wei, Zhao Bi, Wu Ying, Yuan Lixing, Cheng Jingqiu, Shang Huifang
Abstract excerpt
Recently, 17 new Parkinson's disease (PD) risk loci were identified in a genome-wide association studies meta-analysis in Caucasians; however, their association with PD in Chinese patients is largely unknown. Therefore, we performed a replication study of 5 of the most commonly identified candidate variants, including SORBS3 rs2280104, SCN3A rs353116, TOX3 rs4784227, GLAC rs8005172, and ZNF184 rs9468199, in a...