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Relationship between Alzheimer's disease GWAS-linked top hits and risk of Parkinson's disease with or without cognitive decline: a Chinese population-based study.

Neurobiology of aging - 1 Mar 2016

Wang Ya-qin, Tang Bei-sha, Yang Yang, Cui Yi-ting, Kang Ji-feng, Liu Zhen-hua, Li Kai, Sun Qi-ying, Xu Qian, Yan Xin-xiang, Guo Ji-feng

Abstract excerpt

Alzheimer's disease (AD), Parkinson's disease (PD), and cognitive impairment in PD have overlapping clinical and pathological features. To examine whether there is a genetic link for these diseases, we performed a case-control study in Chinese population to evaluate the association of AD genome-wide association studies top hits with both PD and cognitive function in PD, investigating 13 single-nucleotide...

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Identifiers

PMID: 26724962
DOI: 10.1016/j.neurobiolaging.2015.11.024

Genes

ABCA7
BIN1
CLU
PICALM

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