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Article

Smoking Interacts With CHRNA5, a Nicotinic Acetylcholine Receptor Subunit Gene, to Influence the Risk of IBD-Related Surgery.

Inflammatory bowel diseases - 23 Apr 2018

Cushing Kelly C, Chiplunker Adeeti, Li Allie, Sung Yun Ju, Geisman Taylor, Chen Li-Shiun, Cresci Sharon, Gutierrez Alexandra M

Abstract excerpt

Background: Inflammatory bowel disease (IBD) is a chronic luminal disease with genetic and environmental factors affecting phenotype. This study evaluated the relationship between CHRNA5, a nicotinic receptor subunit gene, and smoking in predicting IBD-related surgery as well as the relationship between CHRNA5 and nicotine dependence. Methods: Participants completed a smoking questionnaire and were genotyped for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29688464
DOI: 10.1093/ibd/izx094
PMCID: PMC5994591

Genes

CHRNA5

Provenance

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