Article
Polymorphism in the serotonin transporter gene polymorphisms ( 5-HTTLPR) modifies the association between significant life events and depression in people with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2019
Saul Alice, Taylor Bruce, Simpson Steve, Ponsonby Anne-Louise, Blizzard Leigh, Dwyer Terence, McMorran Brendan, Wood Brenda, van der Mei Ingrid Af
Abstract excerpt
BACKGROUND: In the general population, variation in the serotonin-transporter-linked polymorphic region ( 5-HTTLPR) has been shown to modify the association between stressful events and depression/anxiety. This has not been examined in people with multiple sclerosis (MS). OBJECTIVE: We examined the interaction between significant life events (SLE), 5-HTTLPR and depression/anxiety. METHODS: A population-based...
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