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An endogenous retrovirus insertion disrupting bovine <i>ALKBH8</i> causes a failure-to-thrive syndrome with immunodeficiency associated with juvenile mortality in Brown Swiss cattle

2026-07-10

Abstract excerpt

<h4>ABSTRACT</h4> The Brown Swiss ( BS ) cattle breed is one of the major Swiss dairy breeds. Intensive selection and the widespread use of few elite sires in artificial insemination have increased inbreeding and the occurrence of deleterious recessive alleles in the homozygous state. Analyzing life trajectories in large, genotyped cohorts can identify hidden recessive disorders that are difficult to detect usin...

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Literature Corpus work
9e425bac-dfd7-5f3c-8f69-441c9ba1a4c5
DOI
10.64898/2026.07.09.737535
Open publication

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An endogenous retrovirus insertion disrupting bovine <i>ALKBH8</i> causes a failure-to-thrive syndrome with immunodeficiency associated with juvenile mortality in Brown Swiss cattleDOI 10.64898/2026.07.09.737535
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