Article
Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle.
Nature genetics - 1 Aug 2014
Daetwyler Hans D, Capitan Aurélien, Pausch Hubert, Stothard Paul, van Binsbergen Rianne, Brøndum Rasmus F, Liao Xiaoping, Djari Anis, Rodriguez Sabrina C, Grohs Cécile, Esquerré Diane, Bouchez Olivier, Rossignol Marie-Noëlle, Klopp Christophe, Rocha Dominique, Fritz Sébastien, Eggen André, Bowman Phil J, Coote David, Chamberlain Amanda J, Anderson Charlotte, VanTassell Curt P, Hulsegge Ina, Goddard Mike E, Guldbrandtsen Bernt, Lund Mogens S, Veerkamp Roel F, Boichard Didier A, Fries Ruedi, Hayes Ben J
Abstract excerpt
The 1000 bull genomes project supports the goal of accelerating the rates of genetic gain in domestic cattle while at the same time considering animal health and welfare by providing the annotated sequence variants and genotypes of key ancestor bulls. In the first phase of the 1000 bull genomes project, we sequenced the whole genomes of 234 cattle to an average of 8.3-fold coverage. This sequencing includes data...
Topics
- Amino Acid Sequence
- Animals
- Cattle
- Genome
- Genome-Wide Association Study
- Genotype
- Male
- Molecular Sequence Data