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Article

Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs.

Drug metabolism and pharmacokinetics - 1 Jan 2008

Maeda Kazuya, Sugiyama Yuichi

Abstract excerpt

As the importance of drug transporters in the clinical pharmacokinetics of drugs is recognized, genetic polymorphisms of drug transporters have emerged as one of the determinant factors to produce the inter-individual variability of pharmacokinetics. Many clinical studies have shown the influence of genetic polymorphisms of drug transporters on the pharmacokinetics and subsequent pharmacological and toxicological...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
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Source

Identifiers

PMID: 18762709
DOI: 10.2133/dmpk.23.223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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