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Article

Identification and in Vitro Characterization of Follicle Stimulating Hormone (FSH) Receptor Variants Associated with Abnormal Ovarian Response to FSH

8 Jan 2010

Abstract excerpt

CONTEXT: FSH mediates cyclic follicle growth and development and is widely used for controlled ovarian stimulation in women undergoing infertility treatment. The ovarian response of women to FSH is variable, ranging from poor response to ovarian hyperstimulation. OBJECTIVE: We investigated whether genetic alterations of the FSH receptor (FSHR) contribute to this variability. DESIGN AND PATIENTS: Our approach was...

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PMID: 20061434
DOI: 10.1210/jc.2009-1304

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