Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of follicle-stimulating hormone receptor mutations on female ovarian function and pregnancy outcomes: a systematic review†.

Biology of reproduction - 16 Mar 2026

Qu Zhan, Yang Bei, Miao Yaping, Wang Bei, Shi Han, Cui Chenchen, Zhang Cuilian, Zhao Hua

Abstract excerpt

As a member of the G protein-coupled receptor (GPCR) family, the follicle-stimulating hormone receptor (FSHR) plays a central role in the regulation of female reproduction. By specifically binding to follicle-stimulating hormone (FSH), FSHR regulates the proliferation and differentiation of granulosa cells, follicular development and estradiol (E2) synthesis. In this article, we summarized 37 clinically relevant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ECD gene
Share to FSHR gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Pregnancy

Share to Pregnancy Outcome

Share to Receptors, FSH

Source

Identifiers

PMID: 41416716
DOI: 10.1093/biolre/ioaf283

Genes

FSHR
ECD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of follicle-stimulating hormone receptor mutations on female ovarian function and pregnancy outcomes: a systematic review†.PMID 41416716Read ↗

Mutations and polymorphisms in FSH receptor: functional implications in human reproduction.Semantic proximity Read ↗

Pharmacogenetics of G-protein-coupled receptors variants: FSH receptor and infertility treatment.Semantic proximity Read ↗

Identification and characterization of novel compound heterozygous variants in FSHR causing primary ovarian insufficiency with resistant ovary syndrome.Semantic proximity Read ↗

Mutations and polymorphisms of the FSH receptor (FSHR) gene: clinical implications in female fecundity and molecular biology of FSHR protein and gene.Semantic proximity Read ↗

Follicle-stimulating hormone ligand and receptor mutations, and gonadal dysfunction.Semantic proximity Read ↗

New Natural Inactivating Mutations of the Follicle-Stimulating Hormone Receptor: Correlations between Receptor Function and PhenotypeSemantic proximity Read ↗

Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone ReceptorsSemantic proximity Read ↗

Impact of follicle stimulating hormone receptor variants in fertility.Semantic proximity Read ↗

New natural inactivating mutations of the follicle-stimulating hormone receptor: correlations between receptor function and phenotype.Semantic proximity Read ↗

Identification and in Vitro Characterization of Follicle Stimulating Hormone (FSH) Receptor Variants Associated with Abnormal Ovarian Response to FSHSemantic proximity Read ↗

Genetic variants of gonadotrophins and their receptors: Impact on the diagnosis and management of the infertile patient.Semantic proximity Read ↗

Identification and Characterization of Novel FSHR Copy Number Variations Causing Premature Ovarian Insufficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.