Article
ATP2B1 gene polymorphisms associated with resistant hypertension in the Japanese population.
Journal of clinical hypertension (Greenwich, Conn.) - 1 Apr 2024
Kobayashi Yusuke, Yatsu Keisuke, Haruna Aiko, Kawano Rina, Ozawa Moe, Haze Tatsuya, Komiya Shiro, Suzuki Shota, Ohki Yuki, Fujiwara Akira, Saka Sanae, Hirawa Nobuhito, Toya Yoshiyuki, Tamura Kouichi
Abstract excerpt
Single-nucleotide polymorphisms (SNP) of ATP2B1 gene are associated with essential hypertension but their association with resistant hypertension (RHT) remains unexplored. The authors examined the relationship between ATP2B1 SNPs and RHT by genotyping 12 SNPs in ATP2B1 gene of 1124 Japanese individuals with lifestyle-related diseases. Patients with RHT had inadequate blood pressure (BP) control using three...
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