Article
Functionally Complete Excision of Conditional Alleles in the Mouse Suprachiasmatic Nucleus by Vgat-ires-Cre.
Journal of biological rhythms - 1 Apr 2018
Weaver David R, van der Vinne Vincent, Giannaris E Lela, Vajtay Thomas J, Holloway Kristopher L, Anaclet Christelle
Abstract excerpt
Mice with targeted gene disruption have provided important information about the molecular mechanisms of circadian clock function. A full understanding of the roles of circadian-relevant genes requires manipulation of their expression in a tissue-specific manner, ideally including manipulation with high efficiency within the suprachiasmatic nuclei (SCN). To date, conditional manipulation of genes within the SCN...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
