Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early hemorrhage triggers metabolic responses that build up during prolonged shock.

American journal of physiology. Regulatory, integrative and comparative physiology - 15 Jun 2015

D'Alessandro Angelo, Moore Hunter B, Moore Ernest E, Wither Matthew, Nemkov Travis, Gonzalez Eduardo, Slaughter Anne, Fragoso Miguel, Hansen Kirk C, Silliman Christopher C, Banerjee Anirban

Abstract excerpt

Metabolic staging after trauma/hemorrhagic shock is a key driver of acidosis and directly relates to hypothermia and coagulopathy. Metabolic responses to trauma/hemorrhagic shock have been assayed through classic biochemical approaches or NMR, thereby lacking a comprehensive overview of the dynamic metabolic changes occurring after shock. Sprague-Dawley rats underwent progressive hemorrhage and shock. Baseline...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Energy Metabolism

Share to Mass Spectrometry

Share to Metabolomics

Share to Rats, Sprague-Dawley

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25876652
DOI: 10.1152/ajpregu.00030.2015
PMCID: PMC4469929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early hemorrhage triggers metabolic responses that build up during prolonged shock.PMID 25876652Read ↗

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?Semantic proximity Read ↗

Systemic Metabolic Alterations after Aneurysmal Subarachnoid Hemorrhage: A Plasma Metabolomics ApproachSemantic proximity Read ↗

Metabolomics in severe traumatic brain injury: a scoping reviewSemantic proximity Read ↗

Metabolic Trajectories During Surgical Stress in Patients Undergoing Cardiac SurgerySemantic proximity Read ↗

Metabolic signatures of sepsis in critical care : an individualised approach to diagnosis and managementSemantic proximity Read ↗

Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome.Semantic proximity Read ↗

The Hyperoxia Paradox: The Missing Red Blood Cell Axis in Stress HyperglycaemiaSemantic proximity Read ↗

Metabolic phenotyping of traumatized patients reveals a susceptibility to sepsis.Semantic proximity Read ↗

Global metabolic phenotyping in an experimental laparotomy model of surgical trauma.Semantic proximity Read ↗

Microarray analysis of differentially expressed background genes in rats following hemorrhagic shock.Semantic proximity Read ↗

Metabolic Signatures of Pulmonary Embolism in COVID-19: Insights from Longitudinal Intensive Care Unit ProfilesSemantic proximity Read ↗

Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.