Impact of ABCB1 (rs1045642) polymorphism on antipsychotic-induced extrapyramidal symptoms in Egyptian patients with schizophrenia.

doi:10.1016/j.fct.2026.116181

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Impact of ABCB1 (rs1045642) polymorphism on antipsychotic-induced extrapyramidal symptoms in Egyptian patients with schizophrenia.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Sept 2026

Ahmed Asmaa Mohamed Sayed, Moawad Asmaa Mohammad, Tarek Mennat-Allah, Abdelgwad Marwa, Aboutaleb Alaa Mohamed Ibrahim, Abouelkheir Abrar Roshdy

Abstract excerpt

The ABCB1 polymorphisms may influence risperidone-induced extrapyramidal symptoms (EPS) in schizophrenia. This cross-sectional study examined the relationships among ABCB1 variants, clinical factors, and objective, subjective EPS in 150 patients receiving risperidone at Kasr al-Ainy Hospital, Cairo University, who were genotyped for ABCB1 (rs1045642) and assessed via BARS, SAS, and LUNSERS. The genotype...

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PMID: 42214783
DOI: 10.1016/j.fct.2026.116181

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ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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