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Article

Germline variants in pancreatic cancer patients with a personal or family history of cancer fulfilling the revised Bethesda guidelines.

Journal of gastroenterology - 1 Oct 2018

Ohmoto Akihiro, Morizane Chigusa, Kubo Emi, Takai Erina, Hosoi Hiroko, Sakamoto Yasunari, Kondo Shunsuke, Ueno Hideki, Shimada Kazuaki, Yachida Shinichi, Okusaka Takuji

Abstract excerpt

BACKGROUND: Pancreatic cancer (PC) is categorized as a neoplasm associated with Lynch syndrome; however, the precise proportion of PC patients harboring DNA mismatch repair genes (MMR genes) remains unclear, especially in the Asian population. METHODS: Among 304 Japanese patients with pathologically proven pancreatic ductal adenocarcinoma, we selected 20 (6.6%) patients with a personal or family history involving...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29667044
DOI: 10.1007/s00535-018-1466-y

Genes

ATM
CHEK2
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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