Article
Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy.
Cancer - 15 Apr 2018
Dudley Beth, Karloski Eve, Monzon Federico A, Singhi Aatur D, Lincoln Stephen E, Bahary Nathan, Brand Randall E
Abstract excerpt
BACKGROUND: Approximately 10% of pancreatic adenocarcinoma (PC) cases are attributed to hereditary causes. Individuals with PC and a personal history of another cancer associated with hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) may be more likely to carry germline mutations. METHODS: Participants with PC and a history of cancer were selected from a pancreatic disease registry. Of 1296...
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