Article
Relationship between the Monocyte Chemo-attractant Protein-1 gene rs1024611 A>G Polymorphism and Cancer Susceptibility: A Meta-analysis Involving 14,617 Subjects.
Immunological investigations - 1 Jul 2021
Chen Zhan, Yin Shiping, Zheng Liang, Tang Weifeng, Kang Mingqiang, Wei Wei, Sui Kang
Abstract excerpt
BACKGROUND: Inflammatory and inducible chemokines are the hallmarks of malignancy. Monocyte chemo-attractant protein-1 (MCP-1) is a crucial chemokine implicated in infection and inflammation. Methods: We performed an updated meta-analysis of thirty independent case-control studies with 6,777 cancer cases and 7,840 controls to determine if the MCP-1 gene rs1024611 A > G variant is associated with the risk of...
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