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Article

Repaglinide-irbesartan drug interaction: effects of SLCO1B1 polymorphism on repaglinide pharmacokinetics and pharmacodynamics in Chinese population.

European journal of clinical pharmacology - 1 Aug 2018

Pei Qi, Liu Jun-Yan, Yin Ji-Ye, Yang Guo-Ping, Liu Shi-Kun, Zheng Yi, Xie Pan, Guo Cheng-Xian, Luo Mi, Zhou Hong-Hao, Li Xi, Liu Zhao-Qian

Abstract excerpt

PURPOSE: On account of the potential inhibition of OATP1B1 (organic anion transporting polypeptide) by angiotensin II receptor blockers (ARBs) and the effects of SLCO1B1 (solute carrier organic anion transporter family member) polymorphism, the aim of current study is to assess the impact of ARBs on the pharmacokinetics (PK) and pharmacodynamics (PD) of repaglinide in Chinese healthy volunteers with different...

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Identifiers

PMID: 29748863
DOI: 10.1007/s00228-018-2477-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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