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Article

Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers.

European journal of clinical pharmacology - 1 Jul 2011

He Jiake, Qiu Zhixia, Li Ning, Yu Yang, Lu Yang, Han Deen, Li Tingting, Zhao Di, Sun Wei, Fang Fang, Zheng Jianheng, Fan Hongwei, Chen Xijing

Abstract excerpt

PURPOSE: Repaglinide is commonly used in the treatment of patients with type 2 diabetes mellitus to reduce postprandial hyperglycemia. The objective of this research was to study the effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers. METHODS: A total of 22 healthy young male participants were recruited from a pool of pharmacogenetically...

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PMID: 21327909
DOI: 10.1007/s00228-011-0994-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers.PMID 21327909Read ↗

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