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Article

Performance of DNA methylation‐based biomarkers in the cervical cancer screening program of northern Portugal: A feasibility study

30 Aug 2021

Abstract excerpt

Abstract Cervical cancer remains a health concern. Effective screening programs are critical to reduce the incidence and mortality. High‐risk HPV (hr‐HPV) testing as primary screening tool discloses high sensitivity but suboptimal specificity. Adequate triage tests to reduce unnecessary colposcopy referrals and overdiagnosis/overtreatment are crucial. Hence, we aimed to validate a panel of DNA methylation‐based...

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PMID: 34460099
DOI: 10.1002/ijc.33778

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