Article
A four-gene methylation marker panel as triage test in high-risk human papillomavirus positive patients.
International journal of cancer - 15 Apr 2012
Eijsink J J H, Lendvai Á, Deregowski V, Klip H G, Verpooten G, Dehaspe L, de Bock G H, Hollema H, van Criekinge W, Schuuring E, van der Zee A G J, Wisman G B A
Abstract excerpt
Cervical neoplasia-specific biomarkers, e.g. DNA methylation markers, with high sensitivity and specificity are urgently needed to improve current population-based screening on (pre)malignant cervical neoplasia. We aimed to identify new cervical neoplasia-specific DNA methylation markers and to design and validate a methylation marker panel for triage of high-risk human papillomavirus (hr-HPV) positive patients....
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