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Article

Persistence of the ABCC6 genes and the emergence of the bony skeleton in vertebrates.

Scientific reports - 16 Apr 2018

Parreira Bruna, Cardoso João C R, Costa Rita, Couto Ana Rita, Bruges-Armas Jácome, Power Deborah M

Abstract excerpt

The ATP-binding cassette transporter 6 (ABCC6) gene encodes a cellular transmembrane protein transporter (MRP6) that is involved in the regulation of tissue calcification in mammals. Mutations in ABCC6 are associated with human ectopic calcification disorders. To gain insight into its evolution and involvement in tissue calcification we conducted a comparative analysis of the ABCC6 gene and the related gene ABCC1...

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Source

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Identifiers

PMID: 29662086
DOI: 10.1038/s41598-018-24370-7
PMCID: PMC5902450

Genes

ABCC6
ABCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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