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Article

Origin and Genetic Evolution of the Vertebrate Skeleton

1 Feb 2010

Abstract excerpt

The current understanding of the origin and evolution of the genetic cassette for the vertebrate skeletal system is reviewed. Molecular phylogenetic analyses of fibrillar collagen genes, which encode the main component of both cartilage and mineralized bone, suggest that genome duplications in vertebrate ancestors were essential for producing distinct collagen fibers for cartilage and mineralized bone. Several...

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PMID: 20141417
DOI: 10.2108/zsj.27.119

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