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Article

Cyclic di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions.

The Journal of biological chemistry - 2 Mar 2018

Zeden Merve S, Schuster Christopher F, Bowman Lisa, Zhong Qiyun, Williams Huw D, Gründling Angelika

Abstract excerpt

Cyclic di-adenosine monophosphate (c-di-AMP) is a recently discovered signaling molecule important for the survival of Firmicutes, a large bacterial group that includes notable pathogens such as Staphylococcus aureus However, the exact role of this molecule has not been identified. dacA, the S. aureus gene encoding the diadenylate cyclase enzyme required for c-di-AMP production, cannot be deleted when bacterial...

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Identifiers

PMID: 29326168
DOI: 10.1074/jbc.M117.818716
PMCID: PMC5836111

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Cyclic di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions.PMID 29326168Read ↗

Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus.Semantic proximity Read ↗

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