Spontaneous single nucleotide polymorphism in porcine microRNA-378 seed region leads to functional alteration.

doi:10.1080/09168451.2018.1459175

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Article

Spontaneous single nucleotide polymorphism in porcine microRNA-378 seed region leads to functional alteration.

Bioscience, biotechnology, and biochemistry - 1 Jul 2018

Chai Jie, Chen Lei, Luo Zonggang, Zhang Tinghuan, Chen Li, Lou Pengbo, Sun Wenyang, Long Xi, Lan Jing, Wang Jinyong, Pu Hongzhou, Qiu Jinjie, Shuai Surong, Guo Zongyi

Abstract excerpt

Sequence variation in a microRNA (miRNA) seed region can influence its biogenesis and effects on target mRNAs; however, in mammals, few seed region mutations leading to functional alterations have been reported to date. Here, we report the identification of a single nucleotide polymorphism (SNP) with functional consequence located in the seed region of porcine miR-378. In vitro analysis of this rs331295049 A17G...

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PMID: 29658390
DOI: 10.1080/09168451.2018.1459175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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