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Article

Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes.

Genetics, selection, evolution : GSE - 4 May 2021

Mármol-Sánchez Emilio, Luigi-Sierra María Gracia, Castelló Anna, Guan Dailu, Quintanilla Raquel, Tonda Raul, Amills Marcel

Abstract excerpt

BACKGROUND: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3'UTR binding sites can disrupt canonical conserved miRNA-mRNA pairings, and thus modify gene expression patterns. However, to date such polymorphic sites in miRNA genes and their association with gene expression phenotypes and...

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PMID: 33947333
DOI: 10.1186/s12711-021-00632-3
PMCID: PMC8097994

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