Article
Systemic redox biomarkers and their relationship to prognostic risk markers in autosomal dominant polycystic kidney disease and IgA nephropathy.
Clinical biochemistry - 1 Jun 2018
Tariq Ambreen, Mansoor Mohammad A, Marti Hans-Peter, Jonsson Grete, Slettan Audun, Weeraman Pabasara, Apeland Terje
Abstract excerpt
BACKGROUND: Oxidative stress is evident from an early stage in chronic kidney disease (CKD). Therefore, we investigated redox biomarkers in polycystic kidney disease (ADPKD) and IgA nephropathy (IGAN). METHODS: This is a case-control study with three groups: ADPKD (n = 54), IGAN (n = 58) and healthy controls (n = 86). The major plasma aminothiols with their redox species were examined: homocysteine (Hcy),...
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