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IgA nephropathy is associated with elevated urinary mitochondrial DNA copy numbers

5 Nov 2019

Abstract excerpt

Mitochondrial injury plays important roles in the pathogenesis of various kidney diseases. However, mitochondrial injury in IgA nephropathy (IgAN) remains largely unexplored. Here, we examined the associations among mitochondrial injury, IgAN, and treatment outcomes. We prospectively enrolled patients with IgAN and age-/sex-matched healthy volunteers (HVs) as controls (n = 31 each). Urinary copy numbers of the...

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PMID: 31690796
DOI: 10.1038/s41598-019-52535-5

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