Article
Myotube elasticity of an amyotrophic lateral sclerosis mouse model.
Scientific reports - 12 Apr 2018
Varga Béla, Martin-Fernandez Marta, Hilaire Cécile, Sanchez-Vicente Ana, Areias Julie, Salsac Céline, Cuisinier Frédéric J G, Raoul Cédric, Scamps Frédérique, Gergely Csilla
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects the motor system leading to generalized paralysis and death of patients. The understanding of early pathogenic mechanisms will help to define early diagnostics criteria that will eventually provide basis for efficient therapeutics. Early symptoms of ALS usually include muscle weakness or stiffness. Therefore, mechanical response...
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