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Article

Genomewide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS-Induced Periodontitis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2018

Hiyari Sarah, Green Elissa, Pan Calvin, Lari Soma, Davar Mina, Davis Richard, Camargo Paulo M, Tetradis Sotirios, Lusis Aldons J, Pirih Flavia Q

Abstract excerpt

Periodontitis (PD) is characterized by bacterial infection and inflammation of tooth-supporting structures and can lead to tooth loss. PD affects ∼47% of the US population over age 30 years and has a heritability of about 50%. Although the host immunoinflammatory response and genetic background play a role, little is known of the underlying genetic factors. We examined natural genetic variation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29637625
DOI: 10.1002/jbmr.3440
PMCID: PMC8434897

Genes

CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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