Article
Host susceptibility to periodontitis: mapping murine genomic regions.
Journal of dental research - 1 May 2013
Shusterman A, Durrant C, Mott R, Polak D, Schaefer A, Weiss E I, Iraqi F A, Houri-Haddad Y
Abstract excerpt
Host susceptibility to periodontal infection is controlled by genetic factors. As a step toward identifying and cloning these factors, we generated an A/J x BALB/cJ F2 mouse resource population. A genome-wide search for Quantitative Trait Loci (QTL) associated with periodontitis was performed. We aimed to quantify the phenotypic response of the progenies to periodontitis by microCT analysis, to perform a...
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