Article
Low prevalence of transmitted HIV-1 drug resistance detected by a dried blood spot (DBS)-based next-generation sequencing (NGS) method in newly diagnosed individuals in Cameroon in the years 2015-16.
The Journal of antimicrobial chemotherapy - 1 Jul 2018
Mbunkah Herbert A, Marzel Alex, Schmutz Stefan, Kok Yik Lim, Zagordi Osvaldo, Shilaih Mohaned, Nsanwe Ndi N, Mbu Eyongetah T, Besong Lydia M, Sama Bella A, Orock Emmanuel, Kouyos Roger D, Günthard Huldrych F, Metzner Karin J
Abstract excerpt
Objectives: To determine the most recent prevalence, transmission patterns and risk factors of transmitted drug-resistance mutations (TDRMs) in Cameroon, we initiated a multicentre study monitoring HIV-1 drug resistance in newly HIV-1-diagnosed individuals using a novel next-generation sequencing (NGS) assay applicable to fingerprick dried blood spot (DBS) samples. Methods: Fingerprick DBS samples and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.