Acquired HIV-1 drug resistance to reverse transcriptase and protease inhibitors among people failing antiretroviral therapy in Cameroon and implications for future treatment options.

doi:10.1186/s12981-025-00775-z

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Acquired HIV-1 drug resistance to reverse transcriptase and protease inhibitors among people failing antiretroviral therapy in Cameroon and implications for future treatment options.

AIDS research and therapy - 30 Sept 2025

Fokam Joseph, Anim-Keng Tekoh Tatiana, Pokam Benjamin Thumamo, Chenwi Collins Ambe, Ka'e Aude Christelle, Semengue Ezechiel Ngoufack Jagni, Beloumou Angong Odile Estelle Grâce, Takou Desire, Nka Alex Durand, Djupsa Sandrine, Etame Naomi-Karell, Molimbou Evariste, Ajeh Rogers, Bissek Anne-Cecile Z-K, Colizzi Vittorio, Perno Carlo-Federico, Halle-Ekane Gregory-Edie, Ndembi Nicaise, Ndjolo Alexis

Abstract excerpt

HIV-1 drug resistance (HIVDR) surveillance among individuals failing antiretroviral therapy (ART) is essential to selecting optimal ART-combinations for use in a public health approach in low-middle-income countries (LMICs) where routine HIVDR-testing remains limited. This study describes patterns of acquired drug resistance (ADR) and potentially active drugs for subsequent ART regimens in individuals failing...

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PMID: 41029850
DOI: 10.1186/s12981-025-00775-z
PMCID: PMC12487141

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