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Article

High level of archived and circulating HIV-1 drug resistance mutations in adolescents with a detectable viremia in Cameroon.

The Journal of antimicrobial chemotherapy - 4 Nov 2025

Djiyou Armando B D, Penda Calixte I, Madec Yoann, Ngondi Grace D, Moukoko Astrid, Eboumbou Carole E M, Aghokeng Avelin F

Abstract excerpt

OBJECTIVE: We previously reported a high prevalence of HIV drug resistance mutations (DRMs) among adolescents with a viral load (VL) ≥ 200 copies/mL. In this study, we complement this analysis by simultaneously characterizing circulating and archived viruses in order to obtain a more comprehensive drug resistance profile. METHODS: Using 127 plasma and paired buffy-coat samples collected between February and...

Read the complete abstract on PubMed

Topics

Humans
Adolescent
HIV-1
HIV Infections
Drug Resistance, Viral
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Cameroon

Child

Viral Load

Viremia

Young Adult

Anti-HIV Agents

Mutation

Genotype

Prevalence

Source

Identifiers

PMID: 41047881
DOI: 10.1093/jac/dkaf356

Provenance

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