Article
Scale-up of antiretroviral treatment in sub-Saharan Africa is accompanied by increasing HIV-1 drug resistance mutations in drug-naive patients.
AIDS (London, England) - 13 Nov 2011
Aghokeng Avelin F, Kouanfack Charles, Laurent Christian, Ebong Eugenie, Atem-Tambe Arrah, Butel Christelle, Montavon Celine, Mpoudi-Ngole Eitel, Delaporte Eric, Peeters Martine
Abstract excerpt
OBJECTIVES: To evaluate the frequency and progression over time of the WHO-defined transmitted HIV-1 drug resistance mutations (DRMs) among antiretroviral treatment (ART)-naive HIV-1-infected patients in Cameroon. DESIGN: We analyzed HIV-1 DRM data generated from 369 ART-naive individuals consecutively recruited between 1996 and 2007 in urban and rural areas in Cameroon. METHODS: HIV-1 drug resistance genotyping...
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